Merle and Pearl are still in the clutches of their squirrelnapper. The Gomez family, along with Justin and Sadie, is in hot pursuit. After a wrong turn, they receive a hint from the most unlikely of sources.

Meanwhile, Merle and Pearl are having their own adventure, riding a donkey from Bethlehem to Nazareth under the watchful eye of their abductor. As usual, their hijinks bring laughter and a few surprises―this time in the form of new friends who are also animals. And they can talk!

Will Merle and Pearl finally be rescued? Everyone learns that with God, all things are possible.