In the present study the structure of Fc Receptor-like protein 3 (FCRL) was predicated with the help of Bioinformatics tools and also docking with selected antibiotic such as herbal drug (Acetaminophen and allopathic drug (Mehimazole) was analyzed. Human Fc Receptor-Like protein 3 sequence was retrieved from the Uni-Port protein sequence data base and submitted to the SIB BLAST. The multiple sequence alignment was performed by comparing Fc receptor-like protein 3.