The 45 full papers presented in this book together with 60 short papers were carefully reviewed and selected from 170 submissions.

The papers focus on topics such as: continuous and discrete single- and multi-objective problems, local, global and large-scale optimization, classification in machine learning, optimal control, and applications; computational and applied mathematics (such as approximation theory, computational geometry, computational fluid dynamics, dynamical systems and differential equations, numerical algebra, etc.) and applications in engineering and science; numerical models, methods and software using traditional and emerging high-performance computational tools and paradigms (including the infinity and quantum computing) and their application in artificial intelligence and data science, bioinformatics, economics and management, engineering and technology, mathematical education, number theory and foundations of mathematics, etc.